北海康成-B：截至2026年6月30日止六个月中期业绩公告

CANbridge Pharmaceuticals Inc. 1228 2026630 20266 302025630 20262 15WuXi Biologics HealthCare Venture84,033,6132.382.060%28%12%16.27% ®CAN101IIMPS IIMPS II2018573 •20215®20266309211426.26 •20268®(TFDA) ®CAN108(ALGS)(PFIC)(IBAT)ALGS202395 •20241®2026630920ALGS642.99 •20268 14202691 ®CAN1032018531 •202663042401.75•20267®•®•20268NMPA®212 CAN204(AAV)DMD2018598 ScriptrStitchR™DMD2026AAVStitchR™ CAN301CAN301CAN301(GCase)III®CAN103 20263 303.0562216 20263 30(i)(ii) 20268 5Richard James GregoryGregory 20268 5Richard Arthur MoscickiMoscickiMoscicki50 •202563022.25.725.6%202663027.9Hunterase •2025630104.192.889.1%202663011.32025630101.02025224202522820241231202563097.73.3 •202563018.05.530.5%202663012.52026 •202563016.66.740.3%202663023.3 •202563022.78.236.3%202663030.9® •202563059.2202663037.1 •202563037.49.120266 3028.237.1202563059.2 2026630 67 (37,094)59,238 1,4121,783 (3,536)641 (2,124)2,424 (39,218)61,662 9(0.07)0.14 2026630 202663020251231 143,618110,168 336,995455,341 (193,377)(345,173) (144,616)(289,950) 202663020251231 42,17043,6619,0008,000144144 51,31451,805 (195,930)(341,755) 124034(195,970)(341,789) (195,930)(341,755) 2026630 1. 20181 30 202112 2. 202663034202512 31 202663037,094,0002026630193,377,000195,930,0002026630 1. 2.20266 30 4. 5.®®® 6. 202663012202663012 1. 2. 3. 4. 5. 6. 3. 20251231 202611 9711 4. 6302026202527,94022,248––27,94022,248 2026202563010% ABC 27,94022,248 27,94022,248 5. 11,343104,145 6. 7. 16.5%202516.5%2,000,0008.25%16.5% 20%202520% 25%202525% 21%202521% 8. 20266302025 9. 564,114,9322025424,838,320 2026630 2025630 202663020251231 11. 66 (a)2026630289,5002,289,5000.00001334,000984,000 (b)2021111820266302,000,000 (c)20263 102.3884,033,613200,000,000177,571,000199,000,000176,683,000 2012202120266303®®®1II(LSD)A(ALGS)(PFIC)(FIC)(BIC) (CHARD) CXO ®CAN101 ®(MPS II)(ERT)GCBiopharmaGC PharmaGreen Cross CorporationGC Biopharma®10 (MPS)GAGsII(MPS II)X-2(IDS)GAG0.84/100,000513.4MPS2018MPS IIIDSGAG®MPS IIERT •20209(NMPA)®MPS IIERT•20215®20266309211426.26•20268®(TFDA) ®CAN108 ®Livmarli®(IBAT)®Mirum Pharmaceuticals, Inc.MirumMirum® ®(ALGS)(PFIC)ALGS1/30,0001/50,0002023PFIC70-80%1/50,0001/100,000 ®(FDA)ALGSPFIC IIALGSPFIC®(EMA)ALGSPFIC®(TFDA) •20241231®ALGSPFIC®ALGS •20245®1 •202412®PFIC •202412®1ALGS •20241®2026630920ALGS642.99 •20268 14®202691®ALGSPFIC ®CAN103 ®2025512IIIIIIIII2018 ®® •20253®GMP® •20255®IIII •202512® •202663042401.75 •20267®® •® •20268NMPA®212 CAN106 •CAN106C5(PNH)(MG)CAN106PK/PDCAN106PNHC5 •20192020WuXi Biologics Ireland LimitedPrivus Biologics, LLCPNHC5CAN106 •CAN106FDAMGCAN10650%MG7 •20236CAN106PNH1bCAN10624C53C50.5CAN106 •C5CAN106PNH •CAN106CAN106 CAN204 (AAV)(DMD)201898X205DMD (AAV)DMD(CAN204)Scriptr GlobalStitchR™RNAAAVmidi-Dystrophinmicro-DystrophinDMD •202411ScriptrStitchR™•202512DMD•2026AAVStitchR™DMD CAN301 CAN301CAN301(GCase)III®CAN103 ®CAN301 20262 15WuXi Biologics HealthCare Venture84,033,6132.382.060%28%12%16.27% CRDMO IMARC20232,14820325,4131 2018121202386207 202512025202657 80%2DMD 1)®®®®® 2)BD(First-in-class) CXO 20253®GMP® GC BiopharmMirumCDMO 20258®®®2025 2026202663017.07% 202563022.25.7202663027.9Hunterase 20256306.82.520266309.3 202563015.43.2202663018.7202663066.8%202563069.3% 2025630104.192.8202663011.32025630101.020252 24202522820241231202563097.73.3 202563022.78.220266 3030.9® 202563016.66.7202663023.3 202563018.05.5202663012.52026 20256301.31.220266300.1 20256301.81.620266300.2 (1)(2)(3) (1)2(2)(3) 202663088.129.841.016.31.0202512 3166.6 2026630 202663028.0202512 3115.020266302.65%3.45% 202663042.9%202512 3124.2%2026630 202663014.5%202512319.1% 2026630 2026630202663084,000 2026630 2026630 201972520192021611 54,549,23055,708,000 886,000202663020,767,760 202111182024627 20246 27202462710%10%2024627 2026112286,372,57520264106,372,574202662330,432,79020266305.09% 748,107202663016,578,792 202111182024627 20246 2720246 2710%10%2024627 20261122.32306,372,57520264 102.7246,372,574202662330,346,91520266305.08% 289,500863,23220266 3020,341,917 C1 C.2.1 2012620181 C3 2026630 202663039202512 314115 23.3202563027.7 20266302025630 James Arthur GeraghtyRichard Arthur Moscicki 20266302026630 202663024102410 34 2202663037,094,0002026630193,377,000195,930,0002 22 (www.canbridgepharma.com)(www.hkexnews.hk) 202620269 2026828 Richard Arthur MoscickiJames Arthur Geraghty