美因基因年度报告2025

股份代號: 6667(於開曼群島註冊成立的有限公司) 年度報告2025 2 689102032405993128134135137138140 18171704 779 Third Floor, Century YardCricket Square, P.O. Box 902Grand Cayman, KY1-1103Cayman Islands 401 18171704 www.megagenomics.cn Appleby Global Services (Cayman) Limited71 Fort StreetPO Box 500George TownGrand Cayman KY1-1106Cayman Islands 1617 6667 20251231 2025 247.227.0 ESG 20263 31 2025123126 2021123120202022610 202512 3112797 • •Septin9RNF180/Septin9 •Plus (i)(ii) IVD (i)2025(ii)ApoE2025(iii)BRCA1/BRCA2 (i)(ii)(iii)(iv)(v) ApoE ApoEqPCRApoEApoEApoEϵ4 2025 qPCRMTHFR 2025 miRNA1,500 RT-qPCRNGSNGSLDT RT-qPCR2027 DNA 2025123131,500 qPCRNGS NGSLDT90% qPCR2027 DNA 2025123131,500 qPCRNGS NGSLDT90% qPCR2027 BRCA1/BRCA2 BRCA1/BRCA2PCR 20251231 cfDNADNA20251231 2016 202512315660 65% IVDIVD IVDCROIVD 20251231 IVD CDMOCDMOIVDPCR CRO PCRqPCRNGSPCR IVDNMPAcfDNANMPAApoEIVDBRCA1/BRCA2 PCRqPCRNGSPCR50,000 880PCR2022 247.22024164.250.5%27.09.57.35.51.942.039.32.7 340 20251231247.22024164.283.050.5%120.412.5114.2 20251231117.32024119.379.16.631.7 47.5%72.7%202473.0%65.7%202461.1%52.6%202480.0%27.7% 2025123127.010.9%202445.027.4%20259.57.35.51.9 202020300.8%11.6% ApoEApoE2025 MTHFR2025 65%17.3202512 31127975660 340 IVD 20251231ApoEApoE2025 MTHFR2025 31,500 BRCA1/BRCA2 20251231 cfDNADNA20251231 202412312025 •120.4158.738.3 •12.54.67.9 •114.20.9113.3 202412 3144.984.92025129.8 202420251231119.3117.372.7%47.5% 20241231115.8202579.12024123173.0%202565.7% 202412312.820256.62024123161.1%202552.6% 202412310.7202531.6 202412316.820257.9 202412311.1202512310.4 202412 3136.6202533.7 202412 3119.2202517.3 202412 3122.9202528.0 202412317.3202512319.5 202412310.520252.1 202412311.7202512311.4 202412318.620255.8 2024123145.0202527.0 (i)(ii)(iii)(iv) 202520241231 2022622 16.5 16.9 41.3 20241231490.315.2%20251231415.6 202412312025123113.710.6 2025123118.7202420.72.116.6 2320251231 123120241231 202512313.5%202412 314.7%1.2 (1)(2)(3) 20251231 20251231 20251231 202512 3131.7202433.2 202512310.152024 202512 31206 202111 19202212 2927,272,000D.20221229 2025412026227 20251231 20214222022622 20226221811,961,8001,196.2215.3153.420251231 54201615202186 24 2004 1998320068 20103002577 20152 20153 20161872612 20161120217300231 20175201912 20191201910 1993719998 2013720099 5020181202012 11202012 202132021422202186 2420076201212 20131 20171 45202011202411720218 6 23200311201262012720135201352018120181202011834425 20196 57202131820218 6 24200210 201510 20081 2015212 201712 6 20203 6 20147 47202186 17 201956006942022 20226000625202210600977 2002720077 48202186 172008920174201742015121520171025 2017112018630036420186201912 20186201912Crazy Maple Studio, Inc. 202012024520245202510202510 20047201962820163.10(2) 45202186 1320119201532015720209 (1)(2)(3)(4)(5) 2006720118 45201972216 20089201778247 2017820195 2008720209 432017121912 620163 20163201712 20137 4220178117 20061220111 2011220177 20196 20251231 C1 20251231 20251231 2025123115512 202512 31 C.5.1 2024117 20251231 3.13 20251231 20251231 (i) (ii) (iii) (iv) (v) 108 20251231 202512 31202412 31 2025123120251231 20251231 20251231 20251231 599220251231 (i)(ii)(iii)(iv)(v) (i)(ii)(iii) •••18•• 20251231 A.2.1 20251231 20251231 (i)(ii)(iii) 20251231 20251231 202512 311.5 202512313.2915 64 21 401 18171704 ir@megagenomics.cn (a) (a)(b)(c)(d)(e)(f) (www.hkex.com.hk) (b) (c) (www.megagenomics.cn) (d) (e) www.tricoris.comis-enquiries@hk.tricorglobal.com298013331617 ir@megagenomics.cn401 (f) (g) ESG C2 ESG 20251120251231 ESGESGESGESG2022ESGESGESGESGESGESGESGESG ESGESGESG 2025ESG ESGESGESGESGESGESG 2025ESG2026331 1 1.1 202512 3126202112312020 50,000 20251231340 1.2 1.3 ESGESGESG 1.4 ESG 1.5 19ESGESG 環境 員工 1.能源使用2.水資源使用3.廢棄物管理4.溫室氣體排放5.氣候變化 6.職業健康與安全7.職業發展與機遇8.員工福利9.童工及強制勞工10. 吸納及挽留人才11. 僱員培訓 社區 18. 社區貢獻19. 公益投入 12. 合規經營13. 供應鏈管理14. 投訴處理15. 反貪污16. 知識產權17. 客戶資料保障 ESGESG 2 2.1 2.1.1 DB11/501-2017II50 mg/m320250.45 mg/m320240.45 mg/m3 525.352024571.722.55 50.270.24 SOP-016-SYGL-2.0EHS 2.2 825.892024843.74.0120243.89 18-25 35920242911.7420241.34 2.3 pH69(COD)500 DB11/501-2017 3. 3.1 ESGESG ESGESG 3.2 ESGESG 1155 3.3 4 (1)(2)(3)(4) ESG ESG ESGESG 3.4 20262025 2026 2026 2026 2026 4 4.1 4.1.1 2 2024 4.1.2 4.1.3 202512312062024205 4.1.4 20251231720%202424% 7 4.2 13 2024 4.2.1 EHSEHSEHSEHS 2024 4.2.2 4.3 4.3.1 2025 13.029202414.09 2,68320242,8882,60520242,926 4.4 2024 5 5.1 4112024201 5.2 (ISO15189:2022)352016182021 QA 20242024 5.2.1 (CNAS)ISO15189:2022 5.2.2 HPV 400 5202415 5.3 5.3.1 (i)(ii)(iii)(iv)(v)(vi) (i)(ii)(iii) 5.3.2 5.3.3 5.4 20253215660PCRmiRNAqRT-PCR 202420242024 5.5 221236 2024 6 6.1 100100 20251231 20214222022622 2025123110192031 (1) 20251231247.22024164.283.050.5%120.412.5114.2 2025123