中国生物科技服务2025 年报

GEM GEM GEMGEMGEM GEMGEM 23616193556738385878890167 公司資料 Clarendon House2 Church StreetHamilton HM 11Bermuda 255–257191904–05A Conyers Corporate Services (Bermuda) LimitedClarendon House2 Church StreetHamilton HM 11Bermuda 3382333301–04 www.cbshhk.com 2829 8037 主席報告書 (BNCT)CAR-T BNCT BNCTBNCTBNCT202620212022BNCT 主席報告書 •20262 7 •(BNCT) •StellaPharma CorporationBNCTSTEBORONINE®STEBORONINE®BNCT CAR-T CAR-TCD20 CAR-TLY0071330(European Hematology Association)18(International Conference on Malignant Lymphoma20256 25OX40-heparansulfatebinding facilitates CAR T cell penetration into solid tumors in miceScience translation medicineCART-OX40OX40CAR-T 主席報告書 BNCTCAR-TLY007 1. 2.BNCT 3. 4.CAR-T BNCT 管理層討論及分析 73,503,00070,509,0004.2% 39,158,0008.6%35,782,000 LY007CD20TCAR-TLY007IOX40TCD20B(B-NHL)13BLY007 686,000 NeuCure® 管理層討論及分析 30,600,00037,570,00022.8% 65,000151,0001.3 7,726,0004,940,00010.5%7.0%5,089,000115,000 8,314,00011,774,00029.4% 58,129,00098,141,00040.8%6,342,00022,000,000 17,201,00033,309,00048.4% 管理層討論及分析 DVF Holdco (Cayman) LimitedDVFDVFDVF DVFDVFDVF DVFDVF13,374,0002,584,000 DVF6,731,000 16,922,00027,567,0008,094,000 80,841,000251,854,00067.9%(i)13,824,000(ii)(iii)(iv) 管理層討論及分析 35,000,000272,440,00035,000,000 NeuCure® 180,000,0005,000,000 Dynamic Healthcare Holdings LimitedDynamic Healthcare30,000,00030,000,000Dynamic HealthcareDynamic Healthcare6.25%30,000,000 管理層討論及分析 STEBORONINE® STELLA PHARMA CORPORATIONSTEBORONINE®STEBORONINE®STELLAPHARMA CORPORATIONSTEBORONINE®9000300 LY007(ASCO)66(ASH)1830 CAR-T 管理層討論及分析 Stella Pharma CorporationSTEBORONINE® CAR-TCD20CAR-TLY007 12,083,00018,913,0006,830,000 6,000,00047,100,00044,268,0006,000,00041,635,0008.25%8.25% (i)141,087,00013,259,0004.6%(ii)15,045,00012,722,000 43,519,00024,772,00010%12%10% 管理層討論及分析 4,876,0005,301,0006.7%6% 83,525,00074,746,0000%12%8.25%12% 6,000,00018% 43,960,0007,893,000 702,575,000529,955,000546,830,000287,567,00077.83%54.26%0.230.33 500,000500,000 97,573,115975,731,1500.10 30,660,00043,229,00030,660,000Pillar Biosciences, Inc.PillarZhengu Dianostics Holdings LimitedPillarPillarPillar4.36%8.16%Pillar 管理層討論及分析 Pillar PillarPillarPillar2.80%3.01%3.01%3.01%30,660,00043,229,000PillarPillar9,934,00017,720,0001,838,0003,536,000Pillar12,569,00010,308,000PillarPillarPillar 5% 14,715,000300,225,000 141,087,00013,259,000180,000,00050,000,000 10,030,0005,301,000 管理層討論及分析 6,000,0004,876,00010,496,000780,00027,027,0005,301,000985,0001,060,00033,620,000 22,289,00021,202,00047% 13514151,768,00065,779,000 5% 管理層討論及分析 5%1,500 2,045,0002,231,000 35,000,000 1.201.1142,432,432 董事履歷詳情 5515 Genius Lead Limited529,500,546Genius Earn Limited 6130 44 董事履歷詳情 46300676.SZ 6020301392.SZ002922.SZ 002378.SZ002238.SZ 董事履歷詳情 5220Judge Business SchoolJefferies (Hong Kong)0819.HK 6430XHalcyon GEM17.50A(1) 15 企業管治報告 GEM18.44(2) GEMC1 GEM5.485.67 企業管治報告 GEM5.02D C.1.8 (i)(ii)(iii)(iv) 1618 企業管治報告 1. 企業管治報告 GEM5.05 GEM5.09 A.2.1(a)(b)(c)(d)(e) 企業管治報告 (a)(i)(ii)(b)(c)(d)(e) GEM5.285.29(www.cbshhk.com) 企業管治報告 (a)E.1.2 (b)E.1.2 (a)E.1.2(c)(ii) (b) (c) (d) 1514 GEM5.345.35(www.cbshhk.com) 企業管治報告 GEM (a) (b) (c) (d) (e) (f) (g)GEM 企業管治報告 (a)(b)(c)(d) (www.cbshhk.com) 企業管治報告 51 1.37:10.54:11.07:1 C.2.1 GEM 15 企業管治報告 C.1.4 GEMGEM 80,841,000266,069,000338,012,00012,620,00012,083,000 2 企業管治報告 GEM 7382 GEM 企業管治報告 • • • Committee of Sponsoring Organisations of the Treadway CommissionCOSOCOSOCOSO ••••• 企業管治報告 • • • 5455 D.2.5 (i)(ii) 企業管治報告 1,210,0001,380,000140,000 GEMwww.hkex.com.hkwww.cbshhk.com 企業管治報告 A. 58 255-257191904-05A 21198174(3) B. 255–257191904–05A C. 企業管治報告 (i)(ii)(iii)(iv)(v)(vi)(vii) GEM 環境、社會及管治報告 GEMGEMC2GEMC2(i)(ii)(iii)(iv)(v) 環境、社會及管治報告 環境、社會及管治報告 環境、社會及管治報告 環境、社會及管治報告 •311•358•354•354C•354O (i)(ii)(iii) •57•282•608•480•509•487•527•602•115 環境、社會及管治報告 •486•362•612•619•359•359A•359H•303•303A•303B•161 •201•615•575•405•455 環境、社會及管治報告 ••••• 環境、社會及管治報告 • •25.5• ••• NOXSOXRSPPM6.20.110.466.10.140.45 環境、社會及管治報告 CO2(CH4)(N2O)(CO2e) 1254112 1233 354354O 環境、社會及管治報告 •••••• 70%80% 9.73 環境、社會及管治報告 0.18 5 環境、社會及管治報告 環境、社會及管治報告 (a)(b) 509 環境、社會及管治報告 1.ISO 15189:2012 2. 3. 4. 1. 2. 3.75% 4. 環境、社會及管治報告 ••• 環境、社會及管治報告 480487527602 18 環境、社會及管治報告 1351427% 環境、社會及管治報告 ISO •••••••(GMP) 環境、社會及管治報告 (FMECA)(FTA)(HAZOP) 環境、社會及管治報告 486 362 環境、社會及管治報告 201 董事報告 Clarendon House, 2 Church Street, Hamilton HM 11, Bermuda 255–257191904–05A (a) (b) (c) 董事報告 (d) (e) (f) (i)619(ii)57(iii)362(iv)612(v)41GEM Genius Lead LimitedGenius LeadGenius Earn LimitedGenius Earn (i)(ii)(iii)(iv)(v) 董事報告 8384858629(a) 10 15.30%40.14% 81.93%92.43% 15.30%19.72%40.14%39.83% 81.93%23.17%92.43%62.87% GEM5% 28 董事報告 (a) 38(a) (b) 38(b) (c) 0.66412,575,7570.660.7916.46% 35,000,00033,900,000 8729(b) 董事報告 29(b) 19 44 167168 (i)(ii)(iii)(iv)(v)615 35