State Street Corporation$300,000,000 Floating Rate Senior Notes due 2028$700,000,000Fixed-to-FloatingRate Senior Notes due 2028$1,000,000,000 4.834% Senior Notes due 2030 This is an offering of $300,000,000 aggregate principal amount of floating rate senior notes due 2028 (the “floating rate notes”), $700,000,000 aggregateprincipal amount offixed-to-floatingrate senior notes due 2028 (the“fixed-to-floatingrate notes”), and $1,000,000,000 aggregate principal amount of4.834% senior notes due 2030 (the “2030 notes” and, collectively with the floating rate notes and thefixed-to-floatingrate notes, the “notes”) of StateStreet Corporation (“State Street”). The floating rate notes will mature on April 24, 2028. The floating rate notes will bear interest from and including April 24, 2025 at a floating ratedetermined by reference to the Secured Overnight Funding Rate (“SOFR”) compounded daily over a quarterly interest payment period in accordancewith the specific formula described in this prospectus supplement plus a spread of 0.950%, payable quarterly in arrears. Thefixed-to-floatingrate notes will mature on April 24, 2028. Thefixed-to-floatingrate notes will bear interest from and including April 24, 2025 to,but excluding, April 24, 2027 at a fixed annual rate of 4.543%, payable semiannually in arrears, on April 24 and October 24 of each year, beginning onOctober 24, 2025. From and including April 24, 2027, thefixed-to-floatingrate notes will bear interest at a floating rate determined by reference toSOFR compounded daily over a quarterly interest payment period in accordance with the specific formula described in this prospectus supplement plusa spread of 0.950%, payable quarterly in arrears. The 2030 notes will mature on April 24, 2030. The 2030 notes will bear interest from and including April 24, 2025 at an annual rate of 4.834%, payablesemiannually in arrears, on April 24 and October 24 of each year, beginning on October 24, 2025. We may redeem the 2030 notes in whole or in part, at any time and from time to time, on or after March 24, 2030, at a redemption price equal to 100%of the principal amount of the notes being redeemed, plus accrued and unpaid interest thereon, if any, to, but excluding, the redemption date. We will have the option to redeem the floating rate notes and thefixed-to-floatingrate notes in whole, but not in part, on, and only on, April 24, 2027, ata redemption price equal to 100% of the principal amount of the applicable series of notes being redeemed, plus accrued and unpaid interest thereon, ifany, to, but excluding, the redemption date. See “Description of the Notes—Optional Redemption.” There is no sinking fund for the notes. The notes are unsecured and will rank equally with all other existing and future senior unsecured indebtedness ofState Street. The notes are not bank deposits, and are not insured by the Federal Deposit Insurance Corporation (“FDIC”) or any other governmentalagency, nor are they obligations of, or guaranteed by, a bank. Table of Contents Investing in the notes involves risks. See “Risk Factors” beginning on pageS-14. None of the Securities and Exchange Commission (the “SEC”), any state securities commission, the FDIC or any other regulatory body hasapproved or disapproved of these securities or determined if this prospectus supplement or the accompanying prospectus is truthful orcomplete. Any representation to the contrary is a criminal offense. The notes will not be listed on any securities exchange. Currently, there are no public trading markets for the notes. The underwriters expect to deliverthe notes to purchasers in book-entry form only through the facilities of The Depository Trust Company and its direct participants, including EuroclearBank SA/NV, as operator of the Euroclear System, and Clearstream Banking S.A., on or about April 24, 2025. Joint Book-Running Managers Table of Contents TABLE OF CONTENTS Prospectus Supplement ABOUT THIS PROSPECTUS SUPPLEMENTFORWARD-LOOKING STATEMENTSSUMMARYRISK FACTORSUSE OF PROCEEDSDESCRIPTION OF THE NOTESMATERIAL U.S. FEDERAL TAX CONSEQUENCESUNDERWRITINGLEGAL MATTERSEXPERTSWHERE YOU CAN FIND MORE INFORMATION Prospectus ABOUT THIS PROSPECTUSWHERE YOU CAN FIND MORE INFORMATIONINCORPORATION BY REFERENCEFORWARD-LOOKING STATEMENTSSTATE STREET CORPORATIONUSE OF PROCEEDSDESCRIPTION OF DEBT SECURITIESDESCRIPTION OF PREFERRED STOCKDESCRIPTION OF DEPOSITARY SHARESDESCRIPTION OF COMMON STOCKDESCRIPTION OF PURCHASE CONTRACTS AND UNITSDESCRIPTION OF WARRANTSFORMS OF SECURITIESPLAN OF DISTRIBUTIONLEGAL MATTERSEXPERTS Table of Contents ABOUT THIS PROSPECTUS SUPPLEMENT This document consists of two parts. The first part is this prospectus supplement, which describes the specific terms of this offering. The second part isthe accompanying prospectus, which describes more general information, some of which may not apply to this offering. You should read both thisprospectus supplement and the accompanying prospectus, t