This report provides an overview of the rise and size of Amazon's advertising business, which has become the third-largest in the world after Google and Facebook. In 2021, Amazon's advertising revenue reached $312 billion, up from $22 billion in 2016. The report also highlights the importance of advertising on Amazon, as well as the challenges and strategies for brands and sellers to effectively advertise on the platform. The report includes a category leaderboard for the US and a glossary of digital advertising terms. It also provides insights on return on ad spend (RoAS) by product category, product price, and bidding strategy.