The report "Doing more with less: Defining value in Latin American health systems" highlights the critical need for health investments in Latin America. The report suggests that the pandemic has brought attention to the vulnerabilities of health systems in the region and has catalyzed change by putting pressure on political leaders to invest effectively in the health sector. The report notes that health systems in Latin America have struggled to meet the increased strain of demand for treatment of vector-borne diseases and community-acquired infections, as well as high rates of non-communicable diseases. The report suggests that there are more examples of investments in Latin America that occur in siloes, receive less attention from health policy, or are not widely considered effective. The report recommends a new framework for effective health investment and provides lessons from local practice on implementing effective investment strategies. The report concludes with key takeaways and a call for action to address the health system vulnerabilities in Latin America.