CENTENE CORPORATION Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities ExchangeAct of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has beensubject to such filing requirements for the past 90 days☒Yes☐No Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant toRule 405 of Regulation S-T (232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reportingcompany, or an emerging growth company.See the definitions of "large accelerated filer", "accelerated filer", "smaller reporting company", Accelerated filerSmaller reporting companyEmerging growth company If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complyingwith any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.☐ Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes☐No☒ As of April24, 2026, the registrant had 493,797 thousand shares of common stock outstanding. Part I Financial Information CAUTIONARY STATEMENT ON FORWARD-LOOKING STATEMENTS All statements, other than statements of current or historical fact, contained in this filing are forward-looking statements.Withoutlimiting the foregoing, forward-looking statements often use words such as "believe," "anticipate," "plan," "expect," "estimate,""predict," "intend," "seek," "target," "goal," "potential," "may," "will," "would," "could," "should," "can," "continue," and other similarwords or expressions (and the negative thereof). Centene Corporation and its subsidiaries (Centene, the Company, our or we) intendssuch forward-looking statements to be covered by the safe-harbor provisions for forward-looking statements contained in the PrivateSecurities Litigation Reform Act of 1995, and we are including this statement for purposes of complying with these safe-harborprovisions. In particular, these statements include, without limitation, statements about our expected future operating or financial These forward-looking statements reflect our current views with respect to future events and are based on numerous assumptions andassessments made by us in light of our experience and perception of historical trends, current conditions, business strategies, operatingenvironments, future developments, and other factors we believe appropriate. By their nature, forward-looking statements involveknown and unknown risks and uncertainties and are subject to change because they relate to events and depend on circumstances that All forward-looking statements included in this filing are based on information available to us on the date of this filing. Except as maybe otherwise required by law, we undertake no obligation to update or revise the forward-looking statements included in this filing,whether as a result of new information, future events, or otherwise, afterthe date of this filing.You should not place undue reliance on •our ability to design and price products that are competitive and/or actuarially sound;•our ability to accurately predict and effectively manage health benefits and other operating expenses and reserves, includingfluctuations in medical costs;•rate cuts, insufficient rate changes or other payment reductions or delays by government payors affecting our governmentbusinesses;•the effect of social, economic, and political conditions, geopolitical events and state and federal policies, including theamount and terms of state and federal funding for government-sponsored healthcare programs, including as a result ofchanges in U.S. presidential administrations or Congress;•changes in federal or state laws or regulations, including changes with respect to income tax reform or government healthcareprograms as well as changes with respect to the Patient Protection and Affordable Care Act and the Health Care andEducation Affordability Reconciliation Act (collectively referred to as the ACA) and any regulations enacted thereunder,including the timing and terms of renewal or modification of the Enhanced Advance Premium Tax Credits (eAPTCs) orprogram integrity initiatives that could have the effect of reducing membership or profitability of our products;•unanticipated increased healthcare costs, including due to changes in consumer and provider behaviors, inflation and tariffs;•our ability to maintain or achieve improvement in the Centers for Medicare and Medicaid Services (CMS) Star ratings andmaintain or achieve improvement in other quality scores in each case that could impact reve