This report by the Economist Intelligence Unit explores new and emerging developments in Health Technology Assessment (HTA). The research was conducted during the early stages of the COVID-19 pandemic, but the impact of the pandemic is not a focus of the report. HTA is defined as a multidisciplinary process that summarizes information about the medical, social, economic, and ethical issues related to the use of a health technology in a systematic, transparent, unbiased, and robust manner. HTA is often used to inform decisions about the adoption of new healthcare interventions, including financial reimbursement for providers. The report identifies four key areas of development in HTA: industry engagement and involvement, real-world data and evidence, patient, carer, and citizen involvement, and incorporating patient and carer preferences. The report concludes that HTA is evolving, rather than revolutionizing, and that maintaining organizational agility is crucial for navigating uncertainty in the healthcare industry.