The 2021 Global Threat Intelligence Report emphasizes the importance of cyber-resilience and secure by design solutions in a world of evolving cyber threats. The report discusses the need to re-think infrastructure, engage with partners and customers to build trust, and secure all elements of infrastructure to drive business value and transformation. The report also includes discussions related to trust and the importance of not assigning blind trust to new alliances, partners, or vendors. The report provides analysis of attacks against several industries, including finance, healthcare, education, manufacturing, and technology, and shares insights to help cybersecurity leaders and defenders make informed decisions about where to focus their investments and improvements in security capabilities. The report also helps identify where risks can be reduced and where detection and response capabilities may be improved.