TableofContents (MarkOne) UNITEDSTATES SECURITIESANDEXCHANGECOMMISSION Washington,D.C.20549FORM20-F ☐REGISTRATIONSTATEMENTPURSUANTTOSECTION12(B)OR12(G)OFTHESECURITIESEXCHANGEACTOF1934 OR ☒ANNUALREPORTPURSUANTTOSECTION13OR15(D)OFTHESECURITIESEXCHANGEACTOF1934 ForthefiscalyearendedDecember31,2022. OR ☐TRANSITIONREPORTPURSUANTTOSECTION13OR15(D)OFTHESECURITIESEXCHANGEACTOF1934 Forthetransitionperiodfromto. OR ☐SHELLCOMPANYREPORTPURSUANTTOSECTION13OR15(D)OFTHESECURITIESEXCHANGEACTOF1934 DateofeventrequiringthisshellcompanyreportCommissionfilenumber:001-39328 GenetronHoldingsLimited (ExactnameofRegistrantasspecifiedinitscharter) N/A (TranslationofRegistrant’snameintoEnglish) CaymanIslands (Jurisdictionofincorporationororganization) 1-2/F,Building11,Zone1No.8LifeScienceParkway ChangpingDistrict,Beijing,102206People’sRepublicofChina (Addressofprincipalexecutiveoffices) SizhenWangChiefExecutiveOfficerTel:+86105090-7500 E-mail:sizhen.wang@genetronhealth.comAttheaddressoftheCompanysetforthabove (Name,Telephone,E-mailand/orFacsimilenumberandAddressofCompanyContactPerson) SecuritiesregisteredortoberegisteredpursuanttoSection12(b)oftheAct: Titleofeachclass TradingSymbol Nameofeachexchangeonwhichregistered Americandepositaryshares,each ADSrepresentingfiveordinaryshares,parvalueUS$0.00002pershare Ordinaryshares,parvalueUS$0.00002pershare* GTHTheNasdaqStockMarket LLC(TheNasdaqGlobalMarket) N/ATheNasdaqStockMarket LLC(TheNasdaqGlobalMarket) *Notfortrading,butonlyinconnectionwiththelistingontheNasdaqGlobalMarketofAmericandepositaryshares. SecuritiesregisteredortoberegisteredpursuanttoSection12(g)oftheAct: None (TitleofClass) SecuritiesforwhichthereisareportingobligationpursuanttoSection15(d)oftheAct: None (TitleofClass) Indicatethenumberofoutstandingsharesofeachoftheissuer’sclassesofcapitalorcommonstockasofthecloseoftheperiodcoveredbytheannualreport. 457,743,530ordinaryshares,parvalueUS$0.00002pershare,asofDecember31,2022. Indicatebycheckmarkiftheregistrantisawell-knownseasonedissuer,asdefinedinRule405oftheSecuritiesAct. Yes☐No☒ Ifthisreportisanannualortransitionreport,indicatebycheckmarkiftheregistrantisnotrequiredtofilereportspursuanttoSection13or15(d)oftheSecuritiesExchangeActof1934. Yes☐No☒ Indicatebycheckmarkwhethertheregistrant(1)hasfiledallreportsrequiredtobefiledbySection13or15(d)oftheSecuritiesExchangeActof1934duringthepreceding12months(orforsuchshorterperiodthattheregistrantwasrequiredtofilesuchreports),and(2)hasbeensubjecttosuchfilingrequirementsforthepast90days. Yes☒No☐ IndicatebycheckmarkwhethertheregistranthassubmittedelectronicallyeveryInteractiveDataFilerequiredtobesubmittedpursuanttoRule405ofRegulationS-T(§232.405ofthischapter)duringthepreceding12months(orforsuchshorterperiodthattheregistrantwasrequiredtosubmitsuchfiles). Yes☒No☐ Indicatebycheckmarkwhethertheregistrantisalargeacceleratedfiler,anacceleratedfiler,anon-acceleratedfiler,oranemerginggrowthcompany.Seedefinitionof“largeacceleratedfiler,”“acceleratedfiler,”and“emerginggrowthcompany”inRule12b-2oftheExchangeAct. LargeAcceleratedFiler☐AcceleratedFiler☒Non-acceleratedFiler☐ Emerginggrowthcompany☐ IfanemerginggrowthcompanythatpreparesitsfinancialstatementsinaccordancewithU.S.GAAP,indicatebycheckmarkiftheregistranthaselectednottousetheextendedtransitionperiodforcomplyingwithanyneworrevisedfinancialaccountingstandards†providedpursuanttoSection13(a)oftheExchangeAct.☐ Indicatebycheckmarkwhethertheregistranthasfiledareportonandattestationtoitsmanagement’sassessmentoftheeffectivenessofitsinternalcontroloverfinancialreportingunderSection404(b)oftheSarbanes-OxleyAct(15U.S.C.7262(b))bytheregisteredpublicaccountingfirmthatpreparedorissueditsauditreport. Yes☒No☐ IfsecuritiesareregisteredpursuanttoSection12(b)oftheAct,indicatebycheckmarkwhetherthefinancialstatementsoftheregistrantincludedinthefilingreflectthecorrectionofanerrortopreviouslyissuedfinancialstatements.☐ Indicatebycheckmarkwhetheranyofthoseerrorcorrectionsarerestatementsthatrequiredarecoveryanalysisofincentive-basedcompensationreceivedbyanyoftheregistrant’sexecutiveofficersduringtherelevantrecoveryperiodpursuantto§240.10D-1(b).☐ Indicatebycheckmarkwhichbasisofaccountingtheregistranthasusedtopreparethefinancialstatementsincludedinthisfiling: U.S.GAAP☐InternationalFinancialReportingStandardsasissuedOther☐ bytheInternationalAccountingStandardsBoard☒ If“Other”hasbeencheckedinresponsetothepreviousquestion,indicatebycheckmarkwhichfinancialstatementitemtheregistranthaselectedtofollow. ☐Item17☐Item18 Ifthisisanannualreport,indicatebycheckmarkwhethertheregistrantisashellcompany(asdefinedinRule12b-2oftheExchangeAct). Yes☐No☒ APPLICABLEONLYTOISSUERSINVOLVEDINBANKRUPTCYPROCEEDINGSDURINGTHEPASTFIVEYEARS IndicatebycheckmarkwhethertheregistranthasfiledalldocumentsandreportsrequiredtobefiledbySections12,13or15(d)oftheSecuritiesExchangeActof1934subsequenttothedistributionofsecuritiesunderaplanconfirmedbyacourt. Yes☐No☐ †Theterm“neworrevisedfinancialaccountingstandard”referstoanyupdateissuedbytheFina