UNITEDSTATES SECURITIESANDEXCHANGECOMMISSIONWASHINGTON,D.C.20549 FORM20-F ☐REGISTRATIONSTATEMENTPURSUANTTOSECTION12(b)OR12(g)OFTHESECURITIESEXCHANGEACTOF1934 OR ☒ANNUALREPORTPURSUANTTOSECTION13OR15(d)OFTHESECURITIESEXCHANGEACTOF1934 ForthefiscalyearendedDecember31,2022OR ☐TRANSITIONREPORTPURSUANTTOSECTION13OR15(d)OFTHESECURITIESEXCHANGEACTOF1934 Forthetransitionperiodfromto. OR ☐SHELLCOMPANYREPORTPURSUANTTOSECTION13OR15(d)OFTHESECURITIESEXCHANGEACTOF1934 DateofeventrequiringthisshellcompanyreportCommissionfilenumber:001-40580 SentageHoldingsInc. (ExactNameofRegistrantasSpecifiedinItsCharter) N/A (TranslationofRegistrant’sNameIntoEnglish) CaymanIslands (JurisdictionofIncorporationorOrganization) 501,PlatinumTower233TaicangRoadHuangPu,ShanghaiCity200001People’sRepublicofChina (AddressofPrincipalExecutiveOffices) QiaolingLuTelephone:+86-2153860209 Email:qllu@sentageholdings.com AttheaddressoftheCompanysetforthabove (Name,Telephone,Emailand/orFacsimilenumberandAddressofCompanyContactPerson) SecuritiesregisteredortoberegisteredpursuanttoSection12(b)oftheAct: TitleofEachClassTradingSymbol NameofEachExchangeOnWhichRegistered Ordinaryshares,parvalueUS$0.005pershare SNTG TheNasdaqStockMarketLLC SecuritiesregisteredortoberegisteredpursuanttoSection12(g)oftheAct: None (TitleofClass) SecuritiesforwhichthereisareportingobligationpursuanttoSection15(d)oftheAct: None (TitleofClass) Indicatethenumberofoutstandingsharesofeachoftheissuer’sclassesofcapitalorcommonstockasofthecloseoftheperiodcoveredbytheannualreport: AsofDecember31,2022,therewere2,805,325issuedandoutstandingordinaryshares,parvalueUS$0.005pershare. Indicatebycheckmarkiftheregistrantisawell-knownseasonedissuer,asdefinedinRule405oftheSecuritiesAct.☐Yes☒No Ifthisreportisanannualortransitionreport,indicatebycheckmarkiftheregistrantisnotrequiredtofilereportspursuanttoSection13or15(d)oftheSecuritiesExchangeActof1934.☐Yes☒No Indicatebycheckmarkwhethertheregistrant:(1)hasfiledallreportsrequiredtobefiledbySection13or15(d)oftheSecuritiesExchangeActof1934duringthepreceding12months(orforsuchshorterperiodthattheregistrantwasrequiredtofilesuchreports),and(2)hasbeensubjecttosuchfilingrequirementsforthepast90days.☒Yes☐No IndicatebycheckmarkwhethertheregistranthassubmittedelectronicallyeveryInteractiveDataFilerequiredtobesubmittedpursuanttoRule405ofRegulationS-T(§232.405ofthischapter)duringthepreceding12months(orforsuchshorterperiodthattheregistrantwasrequiredtosubmitsuchfiles).☒Yes☐No Indicatebycheckmarkwhethertheregistrantisalargeacceleratedfiler,anacceleratedfiler,anon-acceleratedfiler,oranemerginggrowthcompany.Seedefinitionof“largeacceleratedfiler,”“acceleratedfiler,”and“emerginggrowthcompany”inRule12b-2oftheExchangeAct. Largeaccelerated☐Acceleratedfiler☐ filer Non-acceleratedfiler ☒Emerginggrowth☒ company IfanemerginggrowthcompanythatpreparesitsfinancialstatementsinaccordancewithU.S.GAAP,indicatebycheckmarkiftheregistranthaselectednottousetheextendedtransitionperiodforcomplyingwithanyneworrevisedfinancialaccountingstandards†providedpursuanttoSection13(a)oftheExchangeAct.☐ †Theterm“neworrevisedfinancialaccountingstandard”referstoanyupdateissuedbytheFinancialAccountingStandardsBoardtoitsAccountingStandardsCodificationafterApril5,2012. Indicatebycheckmarkwhethertheregistranthasfiledareportonandattestationtoitsmanagement’sassessmentoftheeffectivenessofitsinternalcontroloverfinancialreportingunderSection404(b)oftheSarbanes-OxleyAct(15U.S.C.7262(b))bytheregisteredpublicaccountantfirmthatpreparedorissueditsauditreport.☐ Indicatebycheckmarkwhichbasisofaccountingtheregistranthasusedtopreparethefinancialstatementsincludedinthisfiling: U.S.GAAP ☒ InternationalFinancialReportingStandardsasissuedbytheInternationalAccountingStandardsBoard☐ Other☐ If“Other”hasbeencheckedinresponsetothepreviousquestion,indicatebycheckmarkwhichfinancialstatementitemtheregistranthaselectedtofollow.☐Item17☐Item18 Ifthisisanannualreport,indicatebycheckmarkwhethertheregistrantisashellcompany(asdefinedinRule12b-2oftheExchangeAct).☐Yes☒No (APPLICABLEONLYTOISSUERSINVOLVEDINBANKRUPTCYPROCEEDINGSDURINGTHEPASTFIVEYEARS) IndicatebycheckmarkwhethertheregistranthasfiledalldocumentsandreportsrequiredtobefiledbySections12,13or15(d)oftheSecuritiesExchangeActof1934subsequenttothedistributionofsecuritiesunderaplanconfirmedbyacourt.☐Yes☐No TABLEOFCONTENTS INTRODUCTIONii FORWARD-LOOKINGINFORMATIONiii PartI. ITEM1.IDENTITYOFDIRECTORS,SENIORMANAGEMENTANDADVISERS1 ITEM2.OFFERSTATISTICSANDEXPECTEDTIMETABLE1 ITEM4A.UNRESOLVEDSTAFFCOMMENTS92 ITEM3.KEYINFORMATION1 ITEM4.INFORMATIONONTHECOMPANY48 ITEM5.OPERATINGANDFINANCIALREVIEWANDPROSPECTS92 ITEM6.DIRECTORS,SENIORMANAGEMENTANDEMPLOYEES106 ITEM7. MAJORSHAREHOLDERSANDRELATEDPARTYTRANSACTIONS 112 ITEM8. FINANCIALINFORMATION 113 ITEM9. THEOFFERANDLISTING 114 ITEM10. ADDITIONALINFORMATION 114 ITEM11. QUANTITATIVEANDQUALITATIVEDISCLOSURESABOUTMARKETRISK 129 ITEM12. DESCRIPTIONOFSECURITIESOTHERTHANEQUITYSECURITIES 130 PartII.ITEM13. DEFAULTS,DIVIDENDARREARAGESANDDELINQUEN