424B51ea166814-424b5jowellglobal.htmPROSPECTUSSUPPLEMENT FILEDPURSUANTTORULE424(B)(5)REGISTRATIONNO.:333-264109 PROSPECTUSSUPPLEMENT (ToProspectusdatedJuly27,2022) 2,576,600OrdinaryShares JowellGlobalLtd. Pursuanttothisprospectussupplementandtheaccompanyingprospectus,weareofferingtoinvestors2,576,600ordinarysharesoftheCompany(the“Shares”)forapurchasepriceof$1.40pershare.ThisprospectussupplementandtheaccompanyingprospectuscovertheofferandsaleofSharesbytheCompanydirectlytofiveproductdistributorsandbusinesspartnersoftheCompanyinChina. WeexpectthatthedeliveryofthesecuritiesbeingofferedpursuanttothisprospectussupplementandtheaccompanyingprospectuswillbemadeonoraboutOctober25,2022. OurOrdinarySharesarelistedontheNasdaqCapitalMarketunderthesymbol“JWEL”.OnOctober10,2022,thelastreportedsalepriceofourordinarysharesonNasdaqwas$1.49pershare. Wearean“emerginggrowthcompany”asdefinedintheJumpstartOurBusinessActof2012,asamended,and,assuch,willbesubjecttoreducedpubliccompanyreportingrequirements. PerShareTotal Offeringprice$1.40$3,607,240 Wesellthesecuritiesofferedthroughthisprospectussupplementandtheaccompanyingprospectusdirectlytopurchasers.See“PlanofDistribution”beginningonpageS-10ofthisprospectussupplementformoreinformationregardingthesearrangements. InvestinginourOrdinarySharesinvolvesahighdegreeofrisk.BeforebuyinganyOrdinaryShares,youshouldcarefullyconsidertherisksthatwehavedescribedin“SupplementalRiskFactors”beginningonpageS-6ofthisprospectussupplementand“RiskFactors”onpage19oftheaccompanyingprospectus,aswellasthosedescribedinourfilingsundertheSecuritiesExchangeActof1934,asamended(the“ExchangeAct”). INVESTORSPURCHASINGSECURITIESINTHISOFFERINGAREPURCHASINGSECURITIESOFJOWELLGLOBALLTD.(“COMPANY”),ACAYMANISLANDSHOLDINGCOMPANYWITHLIMITEDLIABILITY,RATHERTHANSECURITIESOFCOMPANY’SSUBSIDIARIESORVARIABLEINTERESTENTITYTHATCONDUCTSUBSTANTIVEBUSINESSOPERATIONSINCHINA. WeareaCaymanIslandsholdingcompanywithlimitedliabilityandwithoutmaterialoperationsandourbusinessisconductedbyavariableinterestentity(“VIE”)inChinaandthisstructureinvolvesuniqueriskstoinvestors.WearenotaChineseoperatingcompanyandourbusinessinChinaisconductedthroughcontractualarrangementswiththeVIE.However,theVIEagreementshavenotbeentrulytestedinthecourtsinChina.Chineseregulatoryauthoritiescoulddisallowthisstructure,whichwouldlikelyresultinamaterialchangeinouroperationsand/oramaterialchangeinthevalueofthesecuritiesthatweareofferingforsale,includingthatitcouldcausethevalueofsuchsecuritiestosignificantlydeclineorbecomeworthless.See“RiskFactors—“IftheChinesegovernmentdeterminesthatthecontractualarrangements withtheVIEdonotcomplywithapplicableregulations,ourbusinesscouldbeadverselyaffected.”and“UncertaintiesandquickchangeintheinterpretationandenforcementofChineselawsandregulationswithlittleadvancenoticecouldresultinamaterialandnegativeimpactonourbusinessoperations,decreasethevalueofoursecuritiesandlimitthelegalprotectionsavailabletoyouandus.”intheaccompanyingprospectus. TherearelegalandoperationalrisksassociatedwithbeingbasedinandhavingouroperationsinChina.Recently,thePRCgovernmentinitiatedaseriesofregulatoryactionsandstatementstoregulatebusinessoperationsinChinawithlittleadvancenotice,includingcrackingdownonillegalactivitiesinthesecuritiesmarket,enhancingsupervisionoverChina-basedcompanieslistedoverseasusingvariableinterestentitystructure,adoptingnewmeasurestoextendthescopeofcybersecurityreviews,andexpandingtheeffortsinanti-monopolyenforcement.OnJuly6,2021,theGeneralOfficeoftheCommunistPartyofChinaCentralCommitteeandtheGeneralOfficeoftheStateCounciljointlyissuedanannouncementtocrackdownonillegalactivitiesinthesecuritiesmarketandpromotethehigh-qualitydevelopmentofthecapitalmarket,which,amongotherthings,requirestherelevantgovernmentalauthoritiestostrengthencross-borderoversightoflaw-enforcementandjudicialcooperation,toenhancesupervisionoverChina-basedcompanieslistedoverseas,andtoestablishandimprovethesystemofextraterritorialapplicationofthePRCsecuritieslaws.OnFebruary15,2022,CybersecurityReviewMeasurespublishedbyCyberspaceAdministrationofChinaortheCAC,NationalDevelopmentandReformCommission,MinistryofIndustryandInformationTechnology,MinistryofPublicSecurity,MinistryofStateSecurity,MinistryofFinance,MinistryofCommerce,People’sBankofChina,StateAdministrationofRadioandTelevision,ChinaSecuritiesRegulatoryCommission(“CSRC”),StateSecrecyAdministrationandStateCryptographyAdministrationbecameeffective,whichprovidesthat,CriticalInformationInfrastructureOperators(“CIIOs”)thatintendtopurchaseinternetproductsandservicesandDataProcessingOperators(“DPOs”)engagingindataprocessingactivitiesthataffectormayaffectnationalsecurityshallbesubjecttothecybersecurityreviewbytheCybersecurityReviewOffice.OnNovember14,2021,CACpublishedtheAdministrationMeasuresforCyberDataSecurity(DraftforPublicComments),orthe“CyberDataSecurityMeasure(Draft)”,whichrequirescyberspaceoperatorswithpersonalinformationofmorethan1millionuserswhowanttolistabroadtofileacybersecurityreviewwiththeOfficeofCybersecurityReview.On